Article
Relationship between obesity phenotypes and genetic determinants in a mouse model for juvenile obesity.
Physiological genomics - 16 Sept 2013
Brockmann Gudrun A, Schäfer Nadine, Hesse Claudia, Heise Sebastian, Neuschl Christina, Wagener Asja, Churchill Gary A, Li Renhua
Abstract excerpt
Obesity, a state of imbalance between lean mass and fat mass, is important for the etiology of diseases affected by the interplay of multiple genetic and environmental factors. Although genome-wide association studies have repeatedly associated genes with obesity and body weight, the mechanisms underlying the interaction between the muscle and adipose tissues remain unknown. Using 351 mice (at 10 wk of age) of an...
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