Article
Analysis of vkorc1 polymorphisms in Norway rats using the roof rat as outgroup.
BMC genetics - 24 May 2010
Díaz Juan C, Song Ying, Moore Anthony, Borchert Jeff N, Kohn Michael H
Abstract excerpt
BACKGROUND: Certain mutations in the vitamin K epoxide reductase subcomponent 1 gene (vkorc1) mediate rodent resistance to warfarin and other anticoagulants. Testing for resistance often involves analysis of the vkorc1. However, a genetic test for the roof rat (Rattus rattus) has yet to be developed. Moreover, an available roof rat vkorc1 sequence would enable species identification based on vkorc1 sequence and...
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