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Article

Lumbar disk degeneration disease and aggrecan gene polymorphism in northern Iran.

Biochemical genetics - 1 Aug 2010

Mashayekhi Farhad, Shafiee Gholamreza, Kazemi Masood, Dolati Parviz

Abstract excerpt

Aggrecan is the major component of intervertebral disk matrix proteoglycan with multiple functional domains. To understand the role of aggrecan polymorphism in a part of exon 12 encoding the CS1 domain in lumbar disk degeneration disease, we have analyzed genomic DNA from 71 patients with the disease and 108 healthy individuals in northern Iran. The AGC1 alleles were determined by PCR followed by gel...

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Identifiers

PMID: 20496110
DOI: 10.1007/s10528-010-9350-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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