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CASE-REPORT Association between an ACAN gene variable number tandem repeat polymorphism and lumbar disc herniation: a case control study.

Genetics and molecular research : GMR - 19 Dec 2016

Casa N L L, Casa Junior A J, Melo A V, Teodoro L S, Nascimento G R, Sousa A F, Flausino T C, Brito D, Bergamini R, Minasi L B, da Cruz A D, Vieira T C, Curado M P

Abstract excerpt

We investigated the association between an aggrecan gene (ACAN) polymorphism and lumbar disc herniation (LDH). This was a case-control study with quinquennial age and gender groups. The study comprised 119 men and women aged between 20 and 60 from Goiânia (Brazil). Of these, 39 were allocated to the case group (Ca) and 80 to the control group (Ct). We gathered sociodemographic and clinical data, and peripheral...

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Identifiers

PMID: 28002585
DOI: 10.4238/gmr15048867

Genes

ACAN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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