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Article

The involvement of aggrecan polymorphism in degeneration of human intervertebral disc and articular cartilage.

European cells & materials - 18 Jan 2006

Roughley P, Martens D, Rantakokko J, Alini M, Mwale F, Antoniou J

Abstract excerpt

The functions of the intervertebral disc and of articular cartilage are intimately related to their aggrecan content. Aggrecan is a proteoglycan that interacts with hyaluronan to form large aggregates, which are responsible for the ability of the tissues to resist compressive loads. This function...

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Source

Identifiers

PMID: 16425147

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16425147-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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The involvement of aggrecan polymorphism in degeneration of human intervertebral disc and articular cartilage.PMID 16425147Read ↗

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