Association between the expression of aggrecan and the distribution of aggrecan gene variable number of tandem repeats with symptomatic lumbar disc herniation in Chinese Han of Northern China.

Abstract excerpt

STUDY DESIGN: Case-control study. OBJECTIVE: To examine the association between the expression of aggrecan and the aggrecan gene variable number of tandem repeats (VNTR) polymorphism with symptomatic lumbar disc herniation (LDH) in Chinese Han of Northern China. SUMMARY OF BACKGROUND DATA: Aggrecan fragments have been found in human degenerated discs, and an association between the aggrecan VNTR polymorphism and...

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