Article
Antituberculosis medication as a possible epigenetic factor of Leber's hereditary optic neuropathy.
Clinical & experimental ophthalmology - 1 May 2010
Seo Je Hyun, Hwang Jeong-Min, Park Sung Sup
Abstract excerpt
PURPOSE: To investigate if antituberculosis medication including ethambutol could be a possible epigenetic factor in visual loss in Leber's hereditary optic neuropathy (LHON). METHODS: The authors reviewed the medical records of 46 patients registered at Bundang Seoul National University Hospital from 2002 to 2006, who developed the typical clinical neuro-ophthalmologic features of LHON and possessed a mtDNA...
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