Article
Leber's hereditary optic neuropathy mutations in ethambutol-induced optic neuropathy.
Journal of neurology - 1 Jan 2003
Hwang Jeong-Min, Kim Jiyeon, Park Sung Sup
Abstract excerpt
Primary mitochondrial DNA (mtDNA) mutation at the nt 11778 site in Leber's hereditary optic neuropathy (LHON) has been reported to be present in patients with ethambutol-induced optic neuropathy. To study further this association between LHON and ethambutol-induced optic neuropathy, we tested ethambutol-induced optic neuropathy patients for the presence of the mtDNA mutations at nucleotides (nt)-11778, nt-14484,...
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