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Article

CpG island methylator phenotype of multigene in serum of sporadic breast carcinoma.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Aug 2010

Jing Feng, Yuping Wang, Yong Chen, Jie Luo, Jun Lu, Xuanbing Tang, Lihua Hu

Abstract excerpt

CpG island methylator phenotype (CIMP) involves methylation targeted toward the promoters of multiple genes. We determined a methylation profile of tumor-related genes in serum of sporadic breast cancer (SBC). The multigene methylation was examined by methylation-specific polymerase chain reaction assay in serum of 50 SBCs and 50 paired nontumors, and CIMP+ was defined as having three genes that are concordantly...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20490964
DOI: 10.1007/s13277-010-0040-x

Genes

BRCA1
CDH1
APC
FHIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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