Article
Alterations in function and phenotype of monocytes from patients with septic disease--predictive value and new therapeutic strategies.
Behring Institute Mitteilungen - 1 Feb 1991
Volk H D, Thieme M, Heym S, Döcke W D, Ruppe U, Tausch W, Manger D, Zuckermann S, Golosubow A, Nieter B
Abstract excerpt
Recently we described the predictive value of the proportion of HLA-DR+ peripheral blood monocytes for the clinical outcome of septic disease in immunosuppressed patients (allograft recipients) and surgical patients mostly with peritonitis as septic focus (following perforation of gastrointestinal tract). The experiments described here show that the loss of HLA-class II antigen expression and other phenotypical...
Topics
- Antibodies, Monoclonal
- Antigen-Presenting Cells
- Biomarkers
- Cells, Cultured
- Critical Care
- Cytokines
- Female
- HLA Antigens
- HLA-DR Antigens
- Humans
- Male