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Article

Messenger RNA expression of major histocompatibility complex class II genes in whole blood from septic shock patients*

1 Jan 2005

Abstract excerpt

OBJECTIVE: The decreased expression of human leukocyte antigen (HLA)-DR on monocytes is proposed as a major feature of sepsis-induced immunodepression. The objective of the present study was to investigate, in whole blood from septic shock patients, the messenger RNA (mRNA) expression of a gene panel, which is essential to ensure major histocompatibility complex class II protein structure, transport, and peptide...

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PMID: 15644645
DOI: 10.1097/01.ccm.0000150958.20209.a3

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