Article
Haplotypes of susceptibility to chronic periodontitis in the Interleukin 8 gene do not influence protein level in the gingival crevicular fluid.
Archives of oral biology - 1 Oct 2012
Corbi Sâmia C T, Anovazzi Giovana, Finoti Lívia S, Kim Yeon J, Capela Marisa V, Secolin Rodrigo, Marcaccini Andrea M, Gerlach Raquel F, Orrico Silvana R P, Cirelli Joni A, Scarel-Caminaga Raquel M
Abstract excerpt
OBJECTIVE: Previously, we identified that the ATC/TTC haplotype formed by polymorphisms in the Interleukin-(IL)8 gene conferred susceptibility to chronic periodontitis (CP). The aim of the study was to investigate whether the IL8 haplotype ATC/TTC was associated with the volume of gingival crevicular fluid (GCF), the concentration of interleukin IL-8 in the GCF, as well as periodontal conditions in patients with...
Topics
- Adult
- Case-Control Studies
- Chi-Square Distribution
- Chronic Periodontitis
- Enzyme-Linked Immunosorbent Assay
- Female
- Genetic Predisposition to Disease
- Gingival Crevicular Fluid
- Haplotypes
- Humans
- Interleukin-8
- Linear Models