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PET probes for distinct metabolic pathways have different cell specificities during immune responses in mice

20 May 2010

Abstract excerpt

Clinical tools that measure changes in immune cell metabolism would improve the diagnosis and treatment of immune dysfunction. PET, utilizing probes for specific metabolic processes, detects regions of immune activation in vivo. In this study we investigated the immune cell specificity of PET probes for two different metabolic pathways: [18F]-2-fluorodeoxyglucose ([18F]-FDG) for glycolysis and...

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PMID: 20484820
DOI: 10.1172/jci41250

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