CISH and susceptibility to infectious diseases.

doi:10.1056/NEJMoa0905606

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Article

CISH and susceptibility to infectious diseases.

The New England journal of medicine - 3 Jun 2010

Khor Chiea C, Vannberg Fredrik O, Chapman Stephen J, Guo Haiyan, Wong Sunny H, Walley Andrew J, Vukcevic Damjan, Rautanen Anna, Mills Tara C, Chang Kwok-Chiu, Kam Kai-Man, Crampin Amelia C, Ngwira Bagrey, Leung Chi-Chiu, Tam Cheuk-Ming, Chan Chiu-Yeung, Sung Joseph J Y, Yew Wing-Wai, Toh Kai-Yee, Tay Stacey K H, Kwiatkowski Dominic, Lienhardt Christian, Hien Tran-Tinh, Day Nicholas P, Peshu Nobert, Marsh Kevin, Maitland Kathryn, Scott J Anthony, Williams Thomas N, Berkley James A, Floyd Sian, Tang Nelson L S, Fine Paul E M, Goh Denise L M, Hill Adrian V S

Abstract excerpt

BACKGROUND: The interleukin-2-mediated immune response is critical for host defense against infectious pathogens. Cytokine-inducible SRC homology 2 (SH2) domain protein (CISH), a suppressor of cytokine signaling, controls interleukin-2 signaling. METHODS: Using a case-control design, we tested fo...

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Identifiers

PMID: 20484391
DOI: 10.1056/NEJMoa0905606
PMCID: PMC3646238

Genes

CISH
SRC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20484391-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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