Article
Association of CISH -292A/T genetic variant with hepatitis B virus infection.
Immunogenetics - 1 Apr 2012
Tong Hoang V, Toan Nguyen L, Song Le H, Kremsner Peter G, Kun Jürgen F J, Tp Velavan
Abstract excerpt
Cytokine-inducible SRC homology 2 domain protein (CISH) is a suppressor of cytokine signaling that controls interleukin-2 signaling pathway. We investigated the single nucleotide polymorphism (SNP) -292A>T in 473 Vietnamese hepatitis B virus (HBV) carriers and 416 healthy controls. CISH variants at -292A>T were associated to HBV infection (Allelic: OR, 1.22 95% CI, 1-1.49; P = 0.04; Recessive: OR, 1.69 95% CI...
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