Article
Association between single-nucleotide polymorphism in CISH gene and susceptibility to tuberculosis in Chinese Han population.
Cell biochemistry and biophysics - 1 Apr 2014
Zhao Lan, Chu Haiqing, Xu Xiaogang, Yue Jun, Li Huiping, Wang Minggui
Abstract excerpt
The cytokine-inducible SRC homology 2 domain (CISH) gene is up-regulated by IL-2 in response to infection, and inhibits microbial infection. The objective of the present study was to examine whether genetic variants of CISH (SNPs) are associated with increased susceptibility to tuberculosis (TB) in individuals of Chinese Han ethnicity. We sequenced five previously identified SNPs of CISH in patients with TB or...
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