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Article

[Histone deacetylase inhibitors: highlight on epigenetic regulation].

Bulletin du cancer - 1 Aug 2010

Pécuchet N, Cluzeau T, Thibault C, Mounier N, Vignot S

Abstract excerpt

HDAC, by modifiing relations between DNA and histones, are major proteins of the epigenetic regulation. They play part in the signal transduction and in many cellular processes: cell cycle control, apoptosis, protein degradation, angiogenesis, invasion and cell motility. In several models of cancer HDAC inhibitors (HDACIs) are able to up regulate tumor suppressing gene (p53, p21, pRB...) and to down regulate...

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Identifiers

PMID: 20483706
DOI: 10.1684/bdc.2010.1121

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SRC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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