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Article

Information-theoretic analysis of phenotype changes in early stages of carcinogenesis.

Proceedings of the National Academy of Sciences of the United States of America - 1 Jun 2010

Remacle F, Kravchenko-Balasha Nataly, Levitzki Alexander, Levine R D

Abstract excerpt

Cancer is a multistep process characterized by altered signal transduction, cell growth, and metabolism. To identify such processes in early carcinogenesis we use an information theoretic approach to characterize gene expression quantified as mRNA levels in primary keratinocytes (K) and human papillomavirus 16 (HPV16)-transformed keratinocytes (HF1 cells) from early (E) and late (L) passages and from...

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Identifiers

PMID: 20479229
DOI: 10.1073/pnas.1005283107
PMCID: PMC2890488

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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