Article
Effect modification by vitamin D receptor genetic polymorphisms in the association between cumulative lead exposure and pulse pressure: a longitudinal study.
Environmental health : a global access science source - 13 Jan 2015
Jhun Min A, Hu Howard, Schwartz Joel, Weisskopf Marc G, Nie Linda H, Sparrow David, Vokonas Pantel S, Park Sung Kyun
Abstract excerpt
BACKGROUND: Although the association between lead and cardiovascular disease is well established, potential mechanisms are still poorly understood. Calcium metabolism plays a role in lead toxicity and thus, vitamin D receptor (VDR) polymorphisms have been suggested to modulate the association between lead and health outcomes. We investigated effect modification by VDR genetic polymorphisms in the association...
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