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Article

Association of innate immune IFIH1 gene polymorphisms with dilated cardiomyopathy in a Chinese population.

Immunological investigations - 1 Jan 2014

Dou Qingyu, Peng Ying, Zhou Bin, Lin Jing, Li Yajiao, Yang Hao, Xie Qiu, Li Chunmei, Zhang Lin, Rao Li

Abstract excerpt

The interferon-induced helicase C domain-containing protein 1 (IFIH1) is a cytosolic RNA sensor belonging to the pattern-recognition receptor (PPR) family. Activation of PPRs on innate immune cells is widely believed to control the development of virus-induced autoimmunity in myocarditis and subsequent dilated cardiomyopathy (DCM). We conducted a pilot study to test whether single nucleotide polymorphisms (SNPs)...

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Source

Identifiers

PMID: 24960033
DOI: 10.3109/08820139.2014.909455

Genes

IFIH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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