Article
The polymorphism in aldehyde dehydrogenase-2 gene is associated with elevated plasma levels of high-sensitivity C-reactive protein in the early phase of myocardial infarction.
The Tohoku journal of experimental medicine - 1 Jun 2010
Bian Yuan, Chen Yu-guo, Xu Feng, Xue Li, Ji Wen-qing, Zhang Yun
Abstract excerpt
Aldehyde dehydrogenase-2 (ALDH2) is a key enzyme of alcohol metabolism, catalyzing the conversion of aldehyde to acetic acid. The G-to-A polymorphism in exon 12 of the ALDH2 gene, which causes Glu-to-Lys substitution at codon 504, has been shown to be an independent risk factor for acute myocardial infarction (AMI). We investigated the possible role of the G-to-A polymorphism in the severity of the myocardial...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.