Article
Lack of association between common genetic variation in endothelial lipase (LIPG) and the risk for CAD and DVT.
Atherosclerosis - 1 Aug 2010
Vergeer Menno, Cohn Danny M, Boekholdt S Matthijs, Sandhu Manjinder S, Prins Hester M, Ricketts Sally L, Wareham Nicholas J, Kastelein John J P, Khaw Kay-Tee, Kamphuisen Pieter W, Dallinga-Thie Geesje M
Abstract excerpt
OBJECTIVES: Low levels of high-density lipoprotein cholesterol (HDL-C) are a risk factor for coronary artery disease (CAD) and possibly for deep venous thrombosis (DVT). Endothelial lipase is involved in HDL-C metabolism. Common variants in the endothelial lipase gene (LIPG) have been reported to be associated with HDL-C levels and atherothrombosis, but these findings were not consistent. We determined whether...
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