Article
Association of lipoprotein lipase gene polymorphisms with coronary artery disease.
Journal of the American College of Cardiology - 15 Mar 1999
Anderson J L, King G J, Bair T L, Elmer S P, Muhlestein J B, Habashi J, Mixson L, Carlquist J F
Abstract excerpt
OBJECTIVES: The purpose of this study was to test whether the HindIII (+) and PvuII (-) or (+) restriction enzyme-defined alleles are associated with angiographic coronary artery disease (CAD). BACKGROUND: Lipoprotein lipase (LPL) plays a central role in lipid metabolism, hydrolyzing triglyceride in chylomicrons and very low density lipoproteins. Polymorphic variants of the LPL gene are common and might affect...
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