Article
[The polymorphism of catechol-O-methyltransferase (COMT) and hemochromatosis (HFE) genes in the radiocontaminated regions residents with different chromosome aberration frequency].
Radiatsionnaia biologiia, radioecologiia - 1 Jan 2000
Ivanova T I, Kondrashova T V, Krikunova L I, Smirnova I A, Shentereva N I, Sychenkova N I, Rykova E V, Zharikova I A, Khorokhorina V A, Riabchenko N I, Zamulaeva I A
Abstract excerpt
The association between polymorphisms in genes COMT, HFE that takes part in oxidative stress regulation, and chromosome aberration frequency in lymphocytes was assessed in 278 female residents of radiation polluted regions of Central Russia: Bryansk (322 kBk/m2) and Tula Districts (137Cs - 171 kBk/m2). The C187G, G845A genotyping of HFE and G1947A (H/L) of COMT was done by means of polymerase chain...
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