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Article

Chromosomal aberrations in environmentally exposed population in relation to metabolic and DNA repair genes polymorphisms.

Mutation research - 1 Jul 2007

Sram Radim J, Beskid Olena, Binkova Blanka, Chvatalova Irena, Lnenickova Zdena, Milcova Alena, Solansky Ivo, Tulupova Elena, Bavorova Hana, Ocadlikova Dana, Farmer Peter B

Abstract excerpt

The capital city of Prague is one of the most polluted localities of the Czech Republic. Therefore, the effect of exposure to carcinogenic polycyclic aromatic hydrocarbons (c-PAHs) adsorbed onto respirable air particles (<2.5mum) on chromosomal aberrations was studied in a group of policemen (males, aged 22-50 years) working in the downtown area of Prague and spending daily >8h outdoors (N=53). Age- and...

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Share to Air Pollutants
Share to Carcinogens, Environmental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cytochrome P-450 CYP1A1

Share to Glutathione Transferase

Share to In Situ Hybridization, Fluorescence

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Share to Polycyclic Aromatic Hydrocarbons

Source

Identifiers

PMID: 17418242
DOI: 10.1016/j.mrfmmm.2007.02.019

Genes

EPHX1
GSTP1
GSTM1
GSTT1
MTHFR
NAT2
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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