Article
[The association of TCR-mutant cells with DNA polymorphism in women residing in radiation polluted regions of the Russian Federation].
Radiatsionnaia biologiia, radioecologiia - 1 Jan 2000
Zamulaeva I A, Sal'nikova L E, Ivanova T I, Orlova N V, Smirnova S G, Lapteva N Sh, Chumachenko A G, Belopol'skaia O B, Krikunova L I, Smirnova I A, Saenko A S, Rubanovich A V
Abstract excerpt
Using flow-cytometric method the frequency of lymphocytes beaming mutations at T-cell receptor (TCR) locus was assessed in women residing in radiation polluted regions of Bryansk and Tula Districts. Simultaneously genotyping of the 8 polymorph loci for genes involved in detoxication of xenobiotics and oestrogen metabolism was carried out. The increased TCR-mutant cell frequency was found to be characteristic of...
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