Article
Random forest fishing: a novel approach to identifying organic group of risk factors in genome-wide association studies.
European journal of human genetics : EJHG - 1 Feb 2014
Yang Wei, Charles Gu C
Abstract excerpt
Genome-wide association studies (GWAS) has brought methodological challenges in handling massive high-dimensional data and also real opportunities for studying the joint effect of many risk factors acting in concert as an organic group. The random forest (RF) methodology is recognized by many for its potential in examining interaction effects in large data sets. However, RF is not designed to directly handle GWAS...
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