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Article

Power of data mining methods to detect genetic associations and interactions.

Human heredity - 1 Jan 2011

Molinaro Annette M, Carriero Nicholas, Bjornson Robert, Hartge Patricia, Rothman Nathaniel, Chatterjee Nilanjan

Abstract excerpt

BACKGROUND: Genetic association studies, thus far, have focused on the analysis of individual main effects of SNP markers. Nonetheless, there is a clear need for modeling epistasis or gene-gene interactions to better understand the biologic basis of existing associations. Tree-based methods have been widely studied as tools for building prediction models based on complex variable interactions. An understanding of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 21934324
DOI: 10.1159/000330579
PMCID: PMC3222116

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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