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Article

Gene expression profiling-based identification of molecular subtypes in stage IV melanomas with different clinical outcome.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jul 2010

Jönsson Göran, Busch Christian, Knappskog Stian, Geisler Jürgen, Miletic Hrvoje, Ringnér Markus, Lillehaug Johan R, Borg Ake, Lønning Per Eystein

Abstract excerpt

PURPOSE: The incidence of malignant melanoma is increasing worldwide in fair-skinned populations. Melanomas respond poorly to systemic therapy, and metastatic melanomas inevitably become fatal. Although spontaneous regression, likely due to immune defense activation, rarely occurs, we lack a biological rationale and predictive markers in selecting patients for immune therapy. EXPERIMENTAL DESIGN: We performed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20460471
DOI: 10.1158/1078-0432.CCR-09-2509

Genes

BRAF
NRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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