Article

Dissecting melanoma heterogeneity by integrative genomic analysis for tailored anti-cancer therapy

2018-01-01

Abstract excerpt

Cutaneous melanoma is a highly aggressive disease resistant to conventional treatment and characterized by poor prognosis. Targeted therapies against MAPK pathway and immune checkpoint inhibitors have dramatically improved survival of metastatic melanoma patients but the extent and duration of response are variable. Classification based on gene expression profiling have so far allowed identification of melanoma su...

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Literature Corpus work: 4d79ca33-e518-557a-84d6-c0dbbb51dd08
DOI: 10.21954/ou.ro.0000e44c

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