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Article

Association of TNF-alpha polymorphisms in Crohn disease.

Human immunology - 1 Jan 2005

Zipperlen Katrin, Peddle Lynette, Melay Bill, Hefferton Donna, Rahman Proton

Abstract excerpt

Clinical and molecular studies implicate tumor necrosis factor alpha (TNF-alpha) as a key mediator in the initiation and propagation of Crohn disease (CD). Genetic associations have been documented between promoter polymorphisms of TNF-alpha and CD; however, these associations have not been universally replicated. In this study, we set out to examine the association of five promoter TNF-alpha polymorphisms in CD...

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Source

Identifiers

PMID: 15620462
DOI: 10.1016/j.humimm.2004.10.004

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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