Article
Accumulation of sigmaS due to enhanced synthesis and decreased degradation in acidic phospholipid-deficient Escherichia coli cells.
FEMS microbiology letters - 1 Jun 2010
Uchiyama Junji, Sasaki Yu, Nagahama Hideki, Itou Aya, Matsuoka Satoshi, Matsumoto Kouji, Hara Hiroshi
Abstract excerpt
The Escherichia coli pgsA3 mutation, which causes deficiency in acidic phospholipids, leads to a significant accumulation of sigma(S). This accumulation is partly accounted for by the higher transcription level of rpoS; however, it has also been suggested that the cells accumulate sigma(S) post-transcriptionally. We found that the level of the small regulatory RNA RprA, which is involved in the promotion of rpoS...
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