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Article

Stress sigma factor RpoS degradation and translation are sensitive to the state of central metabolism.

Proceedings of the National Academy of Sciences of the United States of America - 21 Apr 2015

Battesti Aurelia, Majdalani Nadim, Gottesman Susan

Abstract excerpt

RpoS, the stationary phase/stress sigma factor of Escherichia coli, regulates a large cohort of genes important for the cell to deal with suboptimal conditions. Its level increases quickly in the cell in response to many stresses and returns to low levels when growth resumes. Increased RpoS results from increased translation and decreased RpoS degradation. Translation is positively regulated by small RNAs...

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Identifiers

PMID: 25847996
DOI: 10.1073/pnas.1504639112
PMCID: PMC4413282

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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