Article
Unbalanced membrane phospholipid compositions affect transcriptional expression of certain regulatory genes in Escherichia coli.
Journal of bacteriology - 1 May 1997
Inoue K, Matsuzaki H, Matsumoto K, Shibuya I
Abstract excerpt
The amount of porin protein OmpF in the outer membrane of Escherichia coli was reduced to one-third by the pgsA3 mutation that diminishes the amount of phosphatidylglycerol and cardiolipin in the membrane, whereas a cls (cardiolipin synthase) null mutation had no effect. Osmoregulation of OmpF was functional in the pgsA3 mutant. As assessed by the beta-galactosidase activities of lacZ fusions, the ompF expression...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.