Myristic acid auxotrophy caused by mutation of S. cerevisiae myristoyl-CoA:protein N-myristoyltransferase.

doi:10.1083/jcb.113.6.1313

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Article

Myristic acid auxotrophy caused by mutation of S. cerevisiae myristoyl-CoA:protein N-myristoyltransferase.

The Journal of cell biology - 1 Jun 1991

Duronio R J, Rudnick D A, Johnson R L, Johnson D R, Gordon J I

Abstract excerpt

The S. cerevisiae myristoyl-CoA:protein N-myristoyltransferase gene (NMT1) is essential for vegetative growth. NMT1 was found to be allelic with a previously described, but unmapped and unidentified mutation that causes myristic acid (C14:0) auxotrophy. The mutant (nmt1-181) is temperature sensit...

Topics

Acyltransferases
Alleles
Amino Acid Sequence
Base Sequence
Cloning, Molecular
Coenzyme A Ligases
DNA, Fungal
Decanoic Acids
Electrophoresis, Polyacrylamide Gel
Fatty Acids
Kinetics
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Myristic Acids

Phenotype

Repressor Proteins

Saccharomyces cerevisiae

Saccharomyces cerevisiae Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 2045414
DOI: 10.1083/jcb.113.6.1313
PMCID: PMC2289034

Genes

NMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2045414-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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