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Article

Up-regulation of type 2 iodothyronine deiodinase in dilated cardiomyopathy.

Cardiovascular research - 1 Sept 2010

Wang Yuan-Yuan, Morimoto Sachio, Du Cheng-Kun, Lu Qun-Wei, Zhan Dong-Yun, Tsutsumi Takaki, Ide Tomomi, Miwa Yosikazu, Takahashi-Yanaga Fumi, Sasaguri Toshiyuki

Abstract excerpt

AIMS: Thyroid hormone (TH) has prominent effects on the heart, and hyperthyroidism is occasionally found to be a cause of dilated cardiomyopathy (DCM). We aim to explore the potential role of TH in the pathogenesis of DCM. METHODS AND RESULTS: The pathophysiological role of TH in the heart was investigated using a knock-in mouse model of inherited DCM with a deletion mutation DeltaK210 in the cardiac troponin T...

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Identifiers

PMID: 20453157
DOI: 10.1093/cvr/cvq133

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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