Article
Association of bovine neonatal Fc receptor alpha-chain gene (FCGRT) haplotypes with serum IgG concentration in newborn calves.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Dec 2002
Laegreid William W, Heaton Michael P, Keen James E, Grosse William M, Chitko-McKown Carol G, Smith Timothy P L, Keele John W, Bennett Gary L, Besser Thomas E
Abstract excerpt
This report describes allelic variation in FCGRT (which encodes the alpha-chain of FcRn) and its association with variation of IgG concentration in neonatal calves. Five SNPs were identified by sequencing 1305 bp of FCGRT genomic DNA from a multi-breed panel of 96 cattle and 27 founders of a reference population. These SNPs defined five FCGRT haplotypes that were verified by segregation and used to test...
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