Article
No evidence for association between bipolar disorder risk gene variants and brain structural phenotypes.
Journal of affective disorders - 1 Oct 2013
Tesli Martin, Egeland Randi, Sønderby Ida E, Haukvik Unn K, Bettella Francesco, Hibar Derrek P, Thompson Paul M, Rimol Lars Morten, Melle Ingrid, Agartz Ingrid, Djurovic Srdjan, Andreassen Ole A
Abstract excerpt
BACKGROUND: While recent genome-wide association studies have identified several new bipolar disorder (BD) risk variants, structural imaging studies have reported enlarged ventricles and volumetric reductions among the most consistent findings. We investigated whether these genetic risk variants could explain some of the structural brain abnormalities in BD. METHODS: In a sample of 517 individuals (N=121 BD...
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