Article
The clonal composition of Mycobacterium tuberculosis in clinical specimens could be modified by culture.
Tuberculosis (Edinburgh, Scotland) - 1 May 2010
Martín Ana, Herranz Marta, Ruiz Serrano María Jesús, Bouza Emilio, García de Viedma Darío
Abstract excerpt
BACKGROUND: The application of molecular tools has revealed that infection by Mycobacterium tuberculosis (MTB) is more complex than initially assumed. Genotyping is generally performed on cultures. However, there is no information about bacterial clonal complexity in clinical specimens or whether standard culture procedures can modify this complexity. METHODS: An in vitro assay was performed to determine whether...
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