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Article

Population structure of mixed Mycobacterium tuberculosis infection is strain genotype and culture medium dependent.

PloS one - 1 Jan 2013

Hanekom Madeleine, Streicher Elizabeth M, Van de Berg Doreen, Cox Helen, McDermid Cheryl, Bosman Marlein, Gey van Pittius Nicolaas C, Victor Tommie C, Kidd Martin, van Soolingen Dick, van Helden Paul D, Warren Robin M

Abstract excerpt

BACKGROUND: Molecular genotyping methods have shown infection with more than one Mycobacterium tuberculosis strain genotype in a single sputum culture, indicating mixed infection. AIM: This study aimed to develop a PCR-based genotyping tool to determine the population structure of M. tuberculosis strain genotypes in primary Mycobacterial Growth Indicator Tubes (MGIT) and Löwenstein-Jensen (LJ) cultures to...

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Identifiers

PMID: 23936157
DOI: 10.1371/journal.pone.0070178
PMCID: PMC3728311

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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