Article
Abrogation of dominant glucose intolerance in SJL mice by a growth hormone transgene.
Journal of molecular endocrinology - 1 Apr 1991
Bchini O, Mehtali M, Lathe R
Abstract excerpt
Glucose tolerance was studied in transgenic mice (SJL x C57BL/6) expressing human GH under the control of a housekeeping promoter. Parental SJL mice were found to harbour a dominant allele, termed here glid, determining glucose intolerance in pure-bred animals and in F1 hybrids with glucose-tolerant C57BL/6 mice. Blood glucose levels in transgenic SJL x C57BL/6 hybrid mice were well controlled following glucose...
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