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Article

Human cirrhosis: monoclonal regenerative nodules derived from hepatic progenitor cells abutting ductular reaction.

Gastroenterologie clinique et biologique - 1 Jan 2000

Bioulac-Sage P, Balabaud C

Abstract excerpt

Cirrhosis is a premalignant condition leading to hepatocellular carcinoma. Cirrhotic nodules are surrounded by a rim of CK 7/CK19-positive biliary cells termed ductular reaction. Half of all regenerative cirrhotic nodules are thought to be monoclonal by studying the pattern of inactivation of the X-linked human androgen receptor gene (HUMARA). Using a new technique for lineage tracing in human liver based on the...

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Identifiers

PMID: 20430557
DOI: 10.1016/j.gcb.2010.03.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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