Article
Visual screening for JAK2V617F mutation by a disposable dipstick.
Analytical and bioanalytical chemistry - 1 Jul 2010
Konstantou Jessica K, Iliadi Alexandra C, Ioannou Penelope C, Christopoulos Theodore K, Anagnostopoulos Nikolaos I, Kanavakis Emmanuel, Traeger-Synodinos Jan
Abstract excerpt
During the last 5 years, it was discovered that the JAK2V617F somatic mutation is present in virtually all patients with polycythemia vera and a large proportion of patients with essential thrombocythemia, primary myelofibrosis, and refractory anemia with ring sideroblasts and thrombocytosis. As a result, JAK2V617F was incorporated as a new clonal marker in the 2008 revision of the WHO diagnostic criteria....
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