Article
The small heat-shock protein HspL is a VirB8 chaperone promoting type IV secretion-mediated DNA transfer.
The Journal of biological chemistry - 25 Jun 2010
Tsai Yun-Long, Chiang Yin-Ru, Narberhaus Franz, Baron Christian, Lai Erh-Min
Abstract excerpt
Agrobacterium tumefaciens is a plant pathogen that utilizes a type IV secretion system (T4SS) to transfer DNA and effector proteins into host cells. In this study we discovered that an alpha-crystallin type small heat-shock protein (alpha-Hsp), HspL, is a molecular chaperone for VirB8, a T4SS assembly factor. HspL is a typical alpha-Hsp capable of protecting the heat-labile model substrate citrate synthase from...
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