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Article

Protein disaggregation mediated by heat-shock protein Hsp104.

Nature - 1 Dec 1994

Parsell D A, Kowal A S, Singer M A, Lindquist S

Abstract excerpt

The heat-inducible members of the Hsp100 (or Clp) family of proteins share a common function in helping organisms to survive extreme stress, but the basic mechanism through which these proteins function is not understood. Hsp104 protects cells against a variety of stresses, under many physiological conditions, and its function has been evolutionarily conserved, at least from Saccharomyces cerevisiae to...

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PMID: 7984243
DOI: 10.1038/372475a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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