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Article

An open population screening study for HFE gene major mutations proves the low prevalence of C282Y mutation in Central Italy.

Alimentary pharmacology & therapeutics - 15 Aug 2007

Floreani A, Rosa Rizzotto E, Basso D, Navaglia F, Zaninotto M, Petridis I, DI Andrea O, Testa R, Marra M, Baldo V, Chiaramonte M

Abstract excerpt

BACKGROUND: The C282Y mutation in the HFE gene is responsible for most cases of hereditary haemochromatosis. AIM: To investigate the allele frequency of HFE mutations and the associations between mutations and cases of iron overload or liver diseases in an open population of Central Italy. METHODS: A total of 502 individuals over 8 years of age, comprising 203 males and 299 females, who were residents in Arsita...

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Source

Identifiers

PMID: 17661761
DOI: 10.1111/j.1365-2036.2007.03401.x

Genes

HFE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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An open population screening study for HFE gene major mutations proves the low prevalence of C282Y mutation in Central Italy.PMID 17661761Read ↗

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