Article
Association of interleukin-10 gene polymorphism with cachexia in Chinese patients with gastric cancer.
Annals of clinical and laboratory science - 1 Jan 2010
Sun Fengbo, Sun Yunbo, Zhang Dianliang, Zhang Jian, Song Bo, Zheng Hongmei
Abstract excerpt
This study investigated whether the single nucleotide polymorphisms (SNPs) and haplotypes of interleukin-10 (IL-10) were associated with cachexia in 223 Chinese patients with gastric cancer diagnosed by histopathological examination. Genomic DNA was extracted from peripheral blood leukocytes. The SNPs at positions -1082A/G, -819T/C, and -592A/C in the IL-10 gene promoter were analyzed using polymerase chain...
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