Article
Interleukin-10 gene polymorphisms influence susceptibility to cachexia in patients with low-third gastric cancer in a Chinese population.
Molecular diagnosis & therapy - 1 Apr 2010
Sun Fengbo, Sun Yunbo, Yu Zhaohua, Zhang Dianliang, Zhang Jian, Song Bo, Zheng Hongmei
Abstract excerpt
BACKGROUND AND OBJECTIVE: Interleukin (IL)-10 is a pleiotropic cytokine that can both stimulate and suppress the immune response. Previous studies have reported that IL-10 production was significantly elevated in cachectic patients, and it has been confirmed that polymorphisms of the IL10 gene could influence its expression. Therefore, we designed this study to investigate whether polymorphisms of the IL10 gene...
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