Article
[Association of interleukin-10 gene polymorphism with cachexia in patients with gastric cancer].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Nov 2010
Sun Feng-bo, Zhang Dian-liang, Zheng Hong-mei, Song Bo
Abstract excerpt
OBJECTIVE: To investigate whether the single nucleotide polymorphisms (SNPs) at -1082, -819 and -592 of interleukin-10 gene and its haplotype are associated with cachexia in patients with gastric cancer. METHODS: Radioimmunoassay was used to examine the serum levels of IL-10 in 223 patients with gastric cancer. The single nucleotide polymorphisms (SNPs) of IL-10 gene -1082G/A, -819T/C and -592A/C were analyzed...
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