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Exploring the Contribution of Candidate Genes to Artemisinin Resistance in <i>Plasmodium falciparum</i>

27 Apr 2010

Abstract excerpt

The reduced in vivo sensitivity of Plasmodium falciparum has recently been confirmed in western Cambodia. Identifying molecular markers for artemisinin resistance is essential for monitoring the spread of the resistant phenotype and identifying the mechanisms of resistance. Four candidate genes, including the P. falciparum mdr1 (pfmdr1) gene, the P. falciparum ATPase6 (pfATPase6) gene, the 6-kb mitochondrial...

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PMID: 20421395
DOI: 10.1128/aac.00032-10

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